Endometrial Cancer Risk Management & Treatment

Learn about options for endometrial cancer screening, prevention and treatment

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Endometrial Cancer Risk

Every woman is at risk for endometrial cancer; the risk varies based on multiple factors, including:

  • age
  • presence of an inherited mutation
  • personal and family history of cancer
  • other risk factors:

Note that when we use "woman" we are referring to the sex assigned at birth.

Inherited mutations in the genes below have been linked to increased endometrial cancer risk.

Genes Linked to Endometrial Cancer Risk

Uterine serous carcinoma is a rare type of endometrial cancer that is also linked to inherited BRCA mutations. Researchers are studying other inherited mutations that may increase the risk of endometrial cancer.

Other Risk Factors

Diet, weight, exercise, hormone exposure, and medications like tamoxifen can affect endometrial cancer risk in the general population and in people at high risk for cancer. Researchers are studying how much these factors influence risk in people with inherited mutations.

Risk Management and Treatment

People at high risk for endometrial cancer have different options for managing cancer risk, including screening, medications to reduce risk and surgery to reduce risk. National expert guidelines for endometrial cancer risk management are based on your gene mutation and on your level of risk. Click on the button below to learn more about these guidelines. Speak with your healthcare provider to decide on a risk-management plan and schedule that is right for you.

People diagnosed with endometrial cancer may have different treatment options based on the results of genetic testing and biomarker testing. Click on the button below to learn more about these treatment options. Speak with your healthcare provider to decide on a treatment plan that is right for you.

Last updated February 13, 2024